Advancements and Implications of CAR T-Cell Therapy in the Treatment of Hematologic Malignancies

Activity description 

This activity consists of a recorded presentation from the "33rd Annual National Conference" held October 14-16, 2024, in Bloomington, Minn. It is designed to meet the educational needs of nurses, nurse practitioners, pharmacists, pharmacy technicians, psychologists, physicians, PAs and social workers.

This activity will explore advancements in chimeric antigen receptor (CAR) T-cell therapies in treating hematologic malignancies, particularly those of B-cell origin, with a focus on their efficacy and long-term outcomes. An overview of side effects, factors influencing durable remission and strategies to optimize treatment responses to CD19-targeted CAR T cells and B-cell maturation antigen (BCMA)-targeted CAR T cells will be discussed. Participants will also review clinical applications, patient selection protocols, potential toxicities and the management of complications.

Learning Objectives

At the end of this educational activity, participants should be able to:

  • Discuss the efficacy and long-term outcomes of CD19 and BCMA-targeted CAR T-cell therapies in treating various B-cell malignancies and recognize factors associated with durable remission.
  • Describe the unique toxicities associated with CAR T-cell therapies and describe best practices for managing these complications.
  • Evaluate the latest research and innovative strategies in CAR T-cell design and application, including the role of adjunct treatments such as hematopoietic stem cell transplantation.

Provided by
This activity is jointly provided by Optum Health Education.

Commercial support
There was no commercial support received for this activity.

Required hardware/software
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Activity summary
Available credit: 
  • 1.00 ACPE - Pharmacists
  • 1.00 ACPE - Pharmacy Technicians
  • 1.00 AMA - Physicians
  • 1.00 ANCC - Nurses
  • 1.00 APA - Psychologists
  • 1.00 Attendance - General Attendance
  • 1.00 ASWB - Social Workers
Activity opens: 
12/09/2024
Activity expires: 
12/09/2027
Rating: 
0

Presenter
Veronika Bachanova, MD, PhD
Professor of Medicine
Lead of Lymphoma Interdisciplinary Team at University of Minnesota Cell Therapies Clinical Director
Section Head, Malignant Hematology
Division of Hematology, Oncology, and Transplantation
University of Minnesota

Planners
Elizabeth Albert, MD
Clinical Activity Manager
Optum Health Education
Eden Prairie, MN

Sara Fleszar, PharmD, BCOP
Senior Clinical Pharmacist
Optum Health Solutions

Rebecca Gleason, RN, CCM
Activity Manager
Optum Health Education
Eden Prairie, MN

Lisa Latts, MD, MSPH, MBA, FACP
Senior Medical Director, Value-Based Care
Optum
Eden Prairie, MN

Katie L. Lo Coco RN, BSN, CCTC, CCM
Clinical Operations Manager for Transplant Solutions M&R
Optum Health

Disclosures of relevant financial relationships
In accordance with the Accreditation Council for Continuing Medical Education's (ACCME) Standards for Integrity and Independence in Accredited Continuing Education, OptumHealth Education (OHE) requires all those in control of educational content to disclose their financial relationships with ineligible companies within the prior 24 months. Ineligible companies are defined by the ACCME as companies whose primary business is producing, marketing, selling, re-selling, or distributing health care products used by or on patients. Individuals must disclose all financial relationships, regardless of the amount, with ineligible companies and regardless of their view of the relevance of the relationship to the education. OHE ensures that the content is independent of commercial bias

The list below includes individuals that have relevant financial relationships. 
Financial Relationship Key A-Advisory Board CT-Clinical Trial C-Consultant E-Employee G- Grant/Research Support or Funding I-Stocks and Other Ownership Interests S-Speakers’ Bureau O-Other Financial or Material Support

Veronika Bachanova, MD, PhD: Citius, Gamida Cell, Incyte (G); Astra Zeneca (A)

All relevant financial relationships have been mitigated. 

The remaining planners have no financial relationships to disclose.

Method for calculating CE credit
CE credit was calculated by the complexity of content.

Accreditation statement
Joint Accreditation LogoIn support of improving patient care, this activity has been planned and implemented by Optum Health Education. Optum Health Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE) and the American Nurses Credentialing Center (ANCC), to provide continuing education for the health care team.

Credit designation statements

IPCE LogoThis activity was planned by and for the health care team, and learners will receive 1.00 Interprofessional Continuing Education (IPCE) credits for learning and change.

 

Nurses
The participant will be awarded up to 1.00 contact hour(s) of credit for attendance and completion of supplemental materials.

Nurse practitioners
The American Academy of Nurse Practitioners Certification Program (AANPCP) accepts credit from organizations accredited by the ACCME and ANCC.

Pharmacists/Pharmacy technicians
This activity is approved for 1.00 contact hours ([0.10] CEU) in states that recognize ACPE.
Attending the full program will earn 1.00 contact hours.
Unique Activity Number(s):  JA0007123-0000-24-100-H01-P/T

Physicians
Optum Health Education designates this enduring activity for a maximum of 1.00 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

PAs
The American Academy of Physician Assistants (AAPA) accepts credit from organizations accredited by the ACCME.

Psychologists
Optum Health Education is approved by the American Psychological Association (APA) to offer continuing education for psychologists. Optum Health Education maintains responsibility for this program. 1.00 CE hour.

Social workers
ACE LogoAs a Jointly Accredited Organization, Optum Health Education is approved to offer social work continuing education by the Association of Social Work Boards (ASWB) Approved Continuing Education (ACE) program. Organizations, not individual courses, are approved under this program. State and provincial regulatory boards have the final authority to determine whether an individual course may be accepted for continuing education credit. Optum Health Education maintains responsibility for this course. Social workers completing this course receive 1.00 enduring continuing education credits.

Attendance
A certificate of attendance will be provided to learners upon completion of activity requirements, enabling participants to register with licensing boards or associations that have not been pre-approved for credits. To apply for credit types not listed above, participants should use the procedure established by the specific organization with which they wish to obtain credit.

Available Credit

  • 1.00 ACPE - Pharmacists
  • 1.00 ACPE - Pharmacy Technicians
  • 1.00 AMA - Physicians
  • 1.00 ANCC - Nurses
  • 1.00 APA - Psychologists
  • 1.00 Attendance - General Attendance
  • 1.00 ASWB - Social Workers
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