7:00 a.m.

Registration and Continental Breakfast

8:00 a.m.

Welcome and Opening Remarks, F. Sessions Cole, MD, Vice Chairman, Department of Pediatrics, Washington University School of Medicine; CMO, St. Louis Children's Hospital; Mark Leenay, Chief Medical Officer, OptumHealth Care Solutions

8:15 a.m.

Keynote: The Boy Who Saved Thousands of Lives, Reg Green, Nicholas Green Foundation

A 7-year-old boy from California, Nicholas Green, was killed by highway robbers in 1994 while vacationing in Italy with his family. His parents agreed to donate his organs and corneas, which went to seven Italians, four of them teenagers. Their decision captured worldwide attention and led to an increased awareness of the shortage of donors. Organ donations in Italy alone have more than quadrupled so that thousands of people are alive who otherwise would have died. Reg Green will share his family's story and the world's response to their personal tragedy.

9:00 a.m.

What's New in Mechanical Support and Miniature Ventricular Assist Devices (VADs), Scott C. Silvestry, MD, Barnes-Jewish Hospital

Current trends in VADs and mechanical circulatory support will be discussed during this session.

9:45 a.m.

Break

10:00 a.m.

Stem Cell Transplantation Strategies for Multiple Myeloma, Ravi Vij, MD, Barnes-Jewish Hospital

This presentation will encompass an overview of autologous and allogeneic transplantation strategies used to treat multiple myeloma. The importance of posttransplant maintenance therapy will also be highlighted. 

10:45 a.m.

The Center for International Blood and Marrow Transplant Research (CIBMTR) and Stem Cell Therapeutic Outcomes Database (SCTOD)-Past, Present and Future, Janet Brunner, PA-C; Elizabeth Godsey, BS Statistics, Barnes-Jewish Hospital

This presentation will provide a comprehensive overview of past, present, and future trends in blood/marrow and solid organ transplant outcome reporting and how the outcomes may influence referrals. Other therapeutic uses for blood stem cells will also be discussed. 

11:30 a.m.

Unique Perspectives in Infant Lung Transplantation, Stuart Sweet, MD, PhD, St. Louis Children's Hospital

The most common indications for infant lung transplant and the evolving therapies available to enhance patient survival prior to transplant will be reviewed. Posttransplant care will also be discussed, with a focus on outcomes.

12:15 p.m.

Lunch (provided)

1:15 p.m.

Role of the Psychosocial Team in the Pretransplant Process, Suzanne Thompson, PhD; Becki Moss, BS, CCLS; Lisa Mottola-Ernst, MSW, LCSW, St. Louis Children's Hospital

At the conclusion of this presentation, participants will gain a better understanding of the contribution multidisciplinary team members make to the psychological well-being of potential pediatric transplant recipients and their families throughout the transplant evaluation. Psychosocial considerations required for a successful transplant will be discussed.

2:00 p.m.

The Evolution of Therapy for Advanced Pediatric Heart Failure, Charles E. Canter, MD, St. Louis Children's Hospital

Heart transplant is the last option for treatment of heart failure in the pediatric population. This presentation will review the current heart failure treatment modalities, which may delay or negate the necessity for heart transplantation.

2:45 p.m.

Break

3:00 p.m.

Extracorporeal Photopheresis, Brenda J. Grossman, MD, MPH, Barnes-Jewish Hospital

Photopheresis is becoming an accepted therapeutic option for the treatment of chronic rejection posttransplant. Discussion will include description of how the procedure is performed and the potential mechanisms of action.

3:45-4:30 p.m.

Strategies for Liver Transplantation for Cholangiocarcinoma and Hepatocellular Carcinoma (HCC) Beyond Milan Criteria, William Chapman, MD, FACS, Barnes-Jewish Hospital

This presentation will discuss liver transplantation for patients with hepatocellular carcinoma and cholangiocarcinoma, as well as protocols used to manage this patient population.

4:30-6:30 p.m.

Get-Acquainted Reception and Facility Tours

Please join us for a summer reception in the recently dedicated Ellen S. Clark Hope Plaza. Enjoy complimentary drinks and hors d'oeuvres as you visit with exhibitors and get further acquainted with other conference attendees, as well as the staff and employees of St. Louis Children's Hospital, Barnes-Jewish Hospital, and Washington University School of Medicine. Forty-five-minute tours of either St. Louis Children's Hospital or Barnes-Jewish Hospital will be offered at 5 p.m.  Click here for more information

7:00 a.m.

Continental Breakfast

8:00 a.m.

Welcome, Gene Ridolfi, BA, RN, Director, Transplant Services, Barnes-Jewish Hospital; Mark Leenay, Chief Medical Officer, OptumHealth Care Solutions

8:15 a.m.

Pediatric Liver Transplantation for Hepatic Malignancies: Lessons Learned and Future Direction, Christopher Anderson, MD, FACS, St. Louis Children's Hospital

This presentation will encompass an overview of pediatric hepatic malignancies with review of treatment algorithms used to determine candidacy for liver transplant. Single and multicenter patient and graft survival and risk factors for poor outcomes after liver transplant will also be reviewed.

9:00 a.m.

Evolution of Lung Transplantation in the Adult Population, Ramsey Hachem, MD, Barnes-Jewish Hospital

Overview of lung transplantation and its evolution over time, including the impact of the lung allocation system on underlying diagnoses and outcomes after transplantation, the management of graft rejection, and future directions.

9:45 a.m.

Break

10:00 a.m.

Chronic Kidney Disease (CKD) After Solid Organ Transplantation, Paul Hmiel, MD, PhD, St. Louis Children's Hospital

CKD is a common occurrence posttransplant. This presentation will review the disease process and techniques utilized to identify, stage, and manage CKD.

10:45 a.m.

Reduced-Intensity Transplantation (RIT) for Hemoglobinopathy and Other Nonmalignant Disorders: The Pros and Cons, Shalini Shenoy, MD, St. Louis Children's Hospital

RIT, if successful, can provide a safer method of transplantation for children with hemoglobinopathy and other nonmalignant disorders with decreased early and late toxicity. This presentation will provide an overview of the process, current RIT approaches, indications and outcomes of this approach.

11:30 a.m.

Stem Cell Transplantation for Myelodysplastic Syndromes, Peter Westervelt, MD, PhD, Siteman Cancer Center

This presentation will encompass an overview of myelodysplastic syndrome and the role of allogeneic transplantation as a treatment modality. Clinical outcomes and the role of pretransplant therapy will also be discussed. 

12:15 p.m.

Lunch (provided)

1:15 p.m.

Transition from Pediatric to Adult Care: Challenges and Strategies for Success, Kristin A. Kullgren, PhD, St. Louis Children's Hospital; Rebecca Bathon, MSW, LCSW, Barnes-Jewish Hospital

The workshop will describe and delve into the challenges that occur when adolescent transplant recipients and health care teams prepare for the transition to adult care. The speakers will focus on evidence-based models and strategies utilized for a successful transition.

2:00 p.m.

Increasing Utilization of Kidneys to Decrease the Time on the Wait List and Pancreatic Transplantation for Type 1 Diabetes, Jason Wellen, MD, Barnes-Jewish Hospital

This presentation will provide an overview of the utilization of nonstandard criteria donor kidneys to increase the number of transplants for patients on the deceased donor wait list. Pancreatic transplantation for the Type 1 diabetic patient will also be discussed with a focus on benefits and potential risks.

2:45 p.m.

Break

3:00 p.m.

The Impact of Clinical Trials on Transplantation, John F. DiPersio, MD, PhD, Siteman Cancer Center

This presentation will discuss the role of clinical trials in the care of the stem cell transplant recipient. The audience will be provided an overview of the phases of a clinical trial, as well as an explanation of the difference between standard of care versus research as they relate to costs within the transplant process.

3:45 p.m.

Kidney-Pancreas Transplantation, Christina Klein, MD, Barnes-Jewish Hospital

The current strategies for kidney-pancreas transplant management with a focus on criteria for candidacy, surgical techniques used and patient management posttransplant will be outlined during this presentation.

4:30 p.m.

Closing Remarks / Adjourn